Select publications
Boothby-Shoemaker W, Benham V, Paithankar S, Shankar R, Chen B, Bernard JJ. The Relationship between Leptin, the Leptin Receptor and FGFR1 in Primary Human Breast Tumors. Cells. 2020 Oct 1;9(10). doi: 10.3390/cells9102224. PubMed PMID: 33019728; PubMed Central PMCID: PMC7600295.
Bernard JJ, Gallo RL, Krutmann J. Photoimmunology: how ultraviolet radiation affects the immune system. Nat Rev Immunol. 2019 Nov;19(11):688-701. doi: 10.1038/s41577-019-0185-9. Epub 2019 Jun 18. Review. PubMed PMID: 31213673.
Benham V, Bullard B, Dexheimer TS, Bernard MP, Neubig RR, Liby KT, Bernard JJ. Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay. Sci Rep. 2019 Jul 16;9(1):10278. doi: 10.1038/s41598-019-46531-y. PubMed PMID: 31311976; PubMed Central PMCID: PMC6635484.
Benham V, Chakraborty D, Bullard B, Bernard JJ. A role for FGF2 in visceral adiposity-associated mammary epithelial transformation. Adipocyte. 2018 Mar 21:1-8. doi: 10.1080/21623945.2018.1445889. [Epub ahead of print] PubMed PMID: 29561195.
Benham V, Bernard JJ. Why does a high-fat diet increase cancer risk? Future Oncol. 2018 Mar;14(7):583-588. doi: 10.2217/fon-2017-0610. Epub 2018 Feb 7. PubMed PMID: 29411646.
Chakraborty D, Benham V, Jdanov V, Bullard B, Leal AS, Liby KT, Bernard JJ. A BET Bromodomain Inhibitor Suppresses Adiposity-Associated Malignant Transformation. Cancer Prev Res (Phila). 2018 Mar;11(3):129-142. doi: 10.1158/1940-6207.CAPR-17-0262. Epub 2017 Dec 15. PubMed PMID: 29246955.
Chakraborty D, Benham V, Bernard JJ. Elucidating the role of adipose tissue secreted factors in malignant transformation.Adipocyte. 2018 Jan 2;7(1):45-48. doi: 10.1080/21623945.2017.1388971. Epub 2017 Nov 2. PubMed PMID: 29095087; PubMed Central PMCID: PMC5915015.
Chakraborty D, Benham V, Bullard B, Kearney T, Hsia HC, Gibbon D, Demireva EY, Lunt SY, Bernard JJ. Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer. Oncogene. 2017 Aug 7. doi: 10.1038/onc.2017.278. [Epub ahead of print] PubMed PMID: 28783178.
Borkowski AW, Kuo IH, Bernard JJ, Yoshida T, Williams MR, Hung NJ, Yu BD, Beck LA, Gallo RL. Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage. J Invest Dermatol. 2015 Feb;135(2):569-78.
Bernard JJ, Lou YR, Peng QY, Li T, Vakil PR, Ding N, Laskin JD, Dong Z, Conney AH, Lu YP. Parametrial fat tissue from high fat diet-treated SKH-1 mice stimulates transformation of mouse epidermal JB6 cells. J Carcinog Mutagen. 2014 Jul 31;5(183):2157-2518.
Gallo RL, Bernard JJ. Innate immune sensors stimulate inflammatory and immunosuppressive responses to UVB radiation. J Invest Dermatol. 2014 Jun;134(6):1508-11.
Bernard JJ, Lou YR, Peng QY, Li T, Conney AH, Lu YP. Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice. Exp Mol Pathol. 2014 Feb;96(1):126-31.
Bernard JJ, Lou YR, Peng QY, Li T, Lu YP. PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis. PLoS One. 2014 Oct 16;9(10):e109862.
Conney AH, Lou YR, Nghiem P, Bernard JJ, Wagner GC, Lu YP. Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat. Top Curr Chem. 2013;329:61-72.
Bernard JJ, Cowing-Zitron C, Nakatsuji T, Muehleisen B, Muto J, Borkowski AW, Martinez L, Greidinger EL, Yu BD, Gallo RL.Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med. 2012 Aug;18(8):1286-90.
Lu YP, Lou YR, Bernard JJ, Peng QY, Li T, Lin Y, Shih WJ, Nghiem P, Shapses S, Wagner GC, Conney AH. Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9065-70.